Ultram (Tramadol) has been proven effective through controlled clinical trials.
Tramadol has been given in
single oral doses of 50, 75, 100, 150 and 200 mg to patients with
pain following surgical procedures and pain following oral surgery
(extraction of impacted molars). In single-dose models of pain
following oral surgery, pain relief was demonstrated in some
patients at doses of 50 mg and 75 mg. A dose of 100 mg of Tramadol
tended to provide analgesia superior to codeine sulfate 60 mg, but
it was not effective as the combination of aspirin 650 mg with
codeine phosphate 60 mg. In single-dose models of pain following
surgical procedures, 150 mg provided analgesia generally comparable
to the combination of acetaminophen 650 mg with propoxyphene
napsylate 100 mg, with a tendency toward later peak effect. Tramadol
has been studied in three long-term controlled trials involving a
total of 820 patients, with 530 patients receiving Tramadol.
Patients with a variety of chronic painful conditions were studied
in double-blind trials of one to three months duration. Average
daily doses of approximately 250 mg of Tramadol in divided doses
were generally comparable with five doses of acetaminophen 300 mg
with codeine phosphate 30 mg (Tylenol with Codeine #3) daily, five
doses of aspirin 325 mg with codeine phosphate 30 mg daily, or two
to three doses of acetaminophen 500 mg with oxycodone hydrochloride
5 mg (Tylox) daily.
The patients experienced Osteoarthritis symptoms from the following categories:
- pain after surgical procedures
- pain after oral surgery
- Ex: Tramadol after extraction of impacted molar
Ultram Prescriptions